25 per cent of acne occurs for the first time over the age of 26 years and it is sometimes the consequence of tension and/or dehydration. Adult pimples is prevalent also, among people in this band of 25 to 40 especially. Adult acne tends to be more resilient also, with deep, blind pimples that can last for weeks. Many visits to the skin doctor are due to Acne Vulgaris. Although the triggers for adult pimples are unknown, it is thought to possess hormonal roots. Therefore, it could be caused by a hormonal imbalances, pollution, medicines, or stress as stated above. Studies show a primary correlation between hormonal imbalances and outbreaks of acne in women ranging in age group from 30 to 40 years, stress, alcohol and warm foods could aggravate the problem. However, adult acne can be fully controlled by several treatments.In the earliest era of reproductive immunology, immunologists searched for generalized immune suppressive activity to describe why the embryo’s tissue isn’t rejected by the mom during pregnancy. Researchers quickly understood that systemic immune suppression was not compatible with maternal capability to reject paternal stress cells, and it became recognized that some form of active maternal acknowledgement is active in pregnancy.