: Asymptomatic Reactivation of JC Virus in Sufferers Treated with Natalizumab As of 24 July.

Yiping Chen, M.D., Ph http://www.viagra-generics.org/alzheimers-disease.html .D., Evelyn Bord, B.S., Troy Tompkins, B.S., Janice Miller, B.S., Chen S. Tan, M.D., R. Philip Kinkel, M.D., Marion C. Stein, M.D., Raphael P. Viscidi, M.D., Long H. Ngo, Ph.D., and Igor J. Koralnik, M.D.: Asymptomatic Reactivation of JC Virus in Sufferers Treated with Natalizumab As of 24 July, 2009, progressive multifocal leukoencephalopathy , a deadly demyelinating disease of the central nervous system, have been reported in 13 sufferers with multiple sclerosis: 2 who were treated with a combined mix of natalizumab and interferon beta-1a 1-3 and 11 who received natalizumab monotherapy.4-7 One additional patient with Crohn’s disease who was treated with natalizumab died from PML.8 PML is caused by the reactivation of JC virus and affects patients with the acquired immunodeficiency syndrome or leukemia and recipients of organ transplants, but it had never been reported in a person with multiple sclerosis before natalizumab treatment was introduced.